In a first, scientists use designer immune cells to send an autoimmune disease into remission

Five patients with hard-to-treat lupus went into remission after scientists modified their immune cells using a technique normally used to treat cancer. After the single therapy, all five patients with autoimmune disease stopped their standard treatments and have not had a relapse.

This treatment, known as chimeric antigen receptor (CAR) T-cell therapy, needs to be tested in larger groups of lupus patients before it can be approved for widespread use. But if the results hold up in larger trials, the therapy could one day offer relief to people with moderate to severe lupus.

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