CDC warns of serious monkeypox disease as Ohio reports death of monkeypox patient


The US Centers for Disease Control and Prevention issued a new warning to health care providers on Thursday about serious illness in people with monkeypox.

The alert comes as Ohio reported that a person with monkeypox has died, the third known death of a monkeypox patient in the United States.

Ohio listed the death in an update to its online monkeypox outbreak dashboard. No further details were provided, including whether the death was caused by the virus itself or whether other conditions may have contributed.

“CDC is aware of the death of a person who had serious illness and tested positive for monkeypox in Ohio,” Kathleen Conley, a spokeswoman for the Centers for Disease Control and Prevention, told CNN on Thursday. USA CNN has reached out to the Ohio Department of Health for more information.

The first U.S. death from monkeypox was confirmed this month in Los Angeles County. The county public health department and the CDC said the person had a severely weakened immune system and had been hospitalized. No further information will be released, the department said.

A person in Harris County, Texas, who had monkeypox died in August, but the role of the virus in that death has not been confirmed.

Deaths from monkeypox are extremely rare, and infants, pregnant women, and people with weakened immune systems are at greater risk. According to the World Health Organization, among the more than 67,000 cases reported worldwide in the current outbreak, there have been 27 deaths.

More than 25,000 cases of monkeypox have been reported in the United States, but recent trends in cases suggest the outbreak is slowing in the United States.

The drop in the number of cases could be a reflection of the increase in the number of people vaccinated against the virus. This week, the CDC announced that it is expanding eligibility for the Jynneos monkeypox vaccine to people at higher risk who have not been exposed to the virus.

According to data released Wednesday by the CDC, men at high risk of monkeypox because they have sex with other men or because they live with HIV were 14 times more likely to be infected if they weren’t vaccinated compared to those who were. they were at least two weeks old. passed the first dose of the vaccine.

The CDC said Thursday that some people in the United States who were infected with monkeypox during the ongoing outbreak have had “severe manifestations” of the disease, prolonged hospitalizations or “substantial” health problems.

The agency’s health alert notes that severe smallpox can happen to anyone, and most people diagnosed during this outbreak have had mild or moderate disease. Most people whose disease has been severe have had HIV with “substantial immunosuppression,” he says.

Some of the serious illnesses include:

  • Coalescent or necrotic lesions requiring extensive surgical care or amputation of a limb
  • Lesions in sensitive areas such as the mouth, urethra, rectum or vagina that cause severe pain and affect daily activities
  • Intestinal lesions with significant swelling, leading to obstruction
  • Injuries that cause scarring with “significant” effects on areas such as the genitals, intestines or face
  • Multiple organ system involvement and associated conditions including encephalitis, myocarditis, conjunctivitis and corneal ulcers

The advisory urges health care providers to be aware of risk factors for severe monkeypox and says that anyone with suspected or confirmed monkeypox should be tested for HIV. Providers should also check to see if the person’s immune system may be weakened by another condition or medication.

Treatment of monkeypox in people with weakened immune systems should involve stopping any drugs that can affect the immune system, providing antiretroviral therapy for people with HIV, and possibly using drugs such as tecovirimat, known as Tpoxx .

The CDC says people who were exposed to monkeypox through sexual contact should get tested for HIV and other sexually transmitted diseases.

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